The roles of diffusion and perfusion MR imaging in acute stroke management.

نویسنده

  • R E Latchaw
چکیده

mental allergic encephalomyelitis in Lewis rat. Magn Res Med 1992;24:325–334 10. Karlik SJ, Wong C, Gilbert JJ, Noseworthy JH. NMR studies in the relapsing experimental allergic encephalomyelitis (EAE) model of multiple sclerosis in the strain 13 guinea pig. Magn Res Imag 1989;7:463–473 11. Alvord EC Jr, Rose L, Richards T. Chronic experimental allergic encephalomyelitis as a model for multiple sclerosis. In: Martenson R, ed. Myelin: Biology and Chemistry. Boca Raton, Fl: CRC Press, Inc; 1992:849–891 12. Massacesi L, Genain CP, Lee-Parritz D, Letvin NL, Canfield D, Hauser SL. Active and passively induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis. Ann Neurol 1995;37:519–530 13. Genain CP, Hauser SL. Creation of a model for multiple sclerosis in Callithrix jacchus marmosets. J Mol Med 1997;75: 187–197 14. ’t Hart B, Bauer J, Muller H-J, et al. Animal model. Histopathological characterization of magnetic resonance imaging-detectable brain white matter lesions in a primate model of multiple sclerosis. Am J Pathol 1998;153:649–663 15. Nesbit GM, Forbes GS, Scheithauer BW, Okazaki H, Rodriguez M. Multiple sclerosis: histopathologic and MR and/or CT correlation in 37 cases at biopsy and three cases at autopsy. Radiology 1991;180:467–474 16. Bruck W, Bitsch A, Kolenda H, Bruck Y, Stiefel M, Lassmann H. Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology. Ann Neurol 1997;42:783–793 17. Genain CP, Nguyen MH, Letvin NL, et al. Antibody facilitation of multiple sclerosis-like lesions in a non human primate. J Clin Invest 1995;96:2966–2974 18. Genain C, Cannella B, Hauser S, Raine C. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med 1999;5:170–175 19. Genain CP, Roberts T, Davis RL, et al. Prevention of autoimune demyelination by a cAMP-specific phosphodiesterase inhibitor. Proc Natl Acad Sci 1995;92:3601–3605 20. Goodkin D, Rooney W, Sloan R, et al. A serial study of new MS lesions and the white matter from which they arise. Neurology 1998;51:1689–1697

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عنوان ژورنال:
  • AJNR. American journal of neuroradiology

دوره 20 6  شماره 

صفحات  -

تاریخ انتشار 1999